Webb16 sep. 2024 · Proteogenomic characterization reveals the functional impact of genomic alterations • Phosphoproteomics uncovers putative therapeutic targets downstream of KRAS • Multiomics links endothelial cell remodeling and glycolysis to immune exclusion … WebbWe found that PLK1 expression was increased and associated with a worse prognosis in most cancers. Besides, the analysis of immune infiltration levels and ICGs showed their association with PLK1 expression in human pan-cancer. Furthermore, PLK1 was related to TMB, MSI, MMR gene and DNA methylation across cancers.
Howard Spiegel på LinkedIn: Proteogenomic mapping sets stage …
Webb10 sep. 2024 · Proteogenomic analysis of pancreatic cancer subtypes. Pancreatic cancer remains a significant public health problem with an ever-rising incidence of disease. … Webb7 jan. 2024 · 该研究是在国际癌症蛋白质基因组联盟(International Cancer Proteogenome Consortium,ICPC)及国际临床肿瘤蛋白质组学分析联盟(Clinical Proteomic Tumor Analysis Consortium,CPTAC)高质量标准框架下,开展的针对肝内胆管癌大队列的蛋白基因组学分析。 该研究全面揭示了肝内胆管癌中基因突变和染色质变异对蛋白质组和磷酸 … suzuki redcliffe
Abstract 17: Proteogenomic characterization of pancreatic ductal ...
Webb2024年9月16日,美国约翰霍普金斯大学张会(Hui Zhang)、贝勒医学院章冰(Bing Zhang)、圣路易斯华盛顿大学Li Ding等多个机构的合作团队在顶刊Cell发表了题 … WebbThis integrated proteogenomic characterization of PDAC will serve as a valuable resource for the community, paving the way for early detection and identification of novel therapeutic targets. Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient survival. WebbCao, L., et al. Proteogenomic characterization of pancreatic ductal adenocarcinoma. Cell 2024;184(19):5031-5052 e5026. ... C., et al. Proteogenomic insights into the biology and … suzuki red car