Klf5 gastric cancer

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August undefined, 2024

WebMay 3, 2024 · The KLF5, GATA4, and GATA6 genes are independently amplified, and the 3 proteins form a transcription complex to promote the transcription of Hnf4α and tumorigenesis of gastric cancer. 56 Crocin can induce miR320 to target both KLF5 and HIF‐1α to inhibit EMT in gastric cancer cells. 83 Interestingly, miR153 also targets both … WebProtect Your Health: 5 Ways to Prevent Stomach CancerProtect your health and learn about the 5 ways to prevent stomach cancer. In this informative video, we'...

KLF5 promotes proliferation in gastric cancer via regulating p21 …

WebMar 21, 2024 · Clinical resource with information about KLF5, A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33., Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer., and available tests. There are links to practice guidelines and authoritative … WebStomach cancer is a slow-growing cancer that begins in the stomach lining and, if not detected early, can spread to the outer layers of the stomach. Afterwards the stomach cancer can invade through the stomach wall and enter the blood stream or lymph nodes. This allows stomach cancer cells to spread into nearby organs such as the pancreas and ... donate clothes to orphanages

KLF5 promotes proliferation in gastric cancer via regulating p21 …

WebApr 13, 2024 · Case: The population in the case group signed an informed consent form, aged between 18 and 75 years. All subjects underwent endoscopic examination and were confirmed by pathological diagnosis as gastric cancer, including high-grade intraepithelial neoplasia, early gastric cancer, and advanced gastric cancer. WebMar 17, 2024 · Acetylation of KLF5 promotes cancer cell-induced bone metastatic lesions while maintaining the mesenchymal phenotype of cancer cells. a, b Bone metastatic growth of PCa cells (DU 145, ... Xie L, et al. CXCR4, a potential predictive marker for docetaxel sensitivity in gastric cancer. Anticancer Res. 2010; 30:2209–2216. ... WebLi-Fraumeni syndrome [ 82 ] Inherited mutation in TP53 gene.Affected family members at increased risk of bone tumors, breast cancer, leukemia, brain tumors, and sarcomas.17p13. 1 P53 DNA damage response Paget disease [ 83 ] Excessive ... donate clothing flatbush

Cancers Special Issue : Targeted Cancer Therapy

A stem cell marker KLF5 regulates - Nature

WebJul 27, 2024 · KLF5 promotes the proliferation of gastric cancer cells and the expression of metastasis-related molecules. Conclusion KLF4 and KLF5 are of great significance for … WebKLF5 and GATA factors are independently amplified but coexpressed in gastric cancer (GC). (A) Focal genomic amplifications of KLF5, GATA4 and GATA6 in GC. Chromosomal … donate clothes to sheltersWebApr 12, 2024 · Background Metastasis, the leading cause of cancer-related death in patients diagnosed with ovarian cancer (OC), is a complex process that involves multiple biological effects. With the continuous development of sequencing technology, single-cell sequence has emerged as a promising strategy to understand the pathogenesis of ovarian cancer. … city of buckley employment

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Klf5 gastric cancer

Expression and Prognosis Value of the KLF Family Members in ... - Hindawi

WebSep 24, 2013 · KLF5 is downregulated in some types of breast cancer but upregulated in others, and has opposite effects on proliferation in different breast cancer subtypes 90, 91; these seemingly... WebGastric cancer; KLF5; CCL5; CCR5 Introduction Gastric cancer is a leading cause of cancer-related death in the world.1 It was widely considered that genetic mutations and …

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WebJul 11, 2007 · Overall KLF5 was found to be expressed in 45.7% (113/247) of tumor tissues. Moreover, its expression rate was significantly high in early-staged gastric cancer (63.2 vs. 38.0%, p < 0.001), in gastric cancer without lymph node metastasis (54.0 vs. 40.1%, p = 0.04), and in tumors <5 cm in size (53.0 vs. 38.1%, p = 0.02). WebSep 7, 2024 · KLF5 is a member of the Kruppel-like factor, subfamily of zinc finger proteins that are involved in cancers. KLF5 functions as a transcription factor and regulates the diverse protein-coding genes (PCGs) in colorectal cancer (CRC). However, the long non-coding RNAs (lncRNAs) regulated by KLF5 in CRC are currently unknown. Methods

WebKLF5. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. WebKLF5 is involved in the initiation and development of diverse cancers in a context-dependent manner. KLF5 promotes several cancers, such as breast cancer, CRC, bladder cancer, and …

WebThe overexpression of KLF5 in gastric cancer stroma is related to poor patient prognosis. The tissue microarray contains 120 gastric cancer tissues after radical surgery were … WebA suspicious renal mass discovered at the same time as a documented cancer is usually a malignant lesion and may justify combined radical surgical treatment. The authors report the natural history of a suspicious renal mass in a patient with primary gastric tumour corresponding to a MPT syndrome. They recall and discuss the epidemiology ...

WebApr 13, 2024 · 5. Diet. Pickled, salted, and smoked foods can increase the risk of stomach cancer. Fresh fruits and vegetables can lower the risks. 6. Helicobacter Pylori Infection. This bacteria causes ...

WebOct 27, 2024 · KLF5 has been reported as a lineage-survival oncogene whose expression is upregulated in specific cancer types, such as squamous carcinoma (e.g., head and neck … donate clothing bergenfield njWebDec 15, 2024 · The analysis reveals that the KLF5 DNA recognition sequence is one of the top three motifs enriched in chromatin accessible regions found in squamous, colorectal, … donate clothing for moneyWeb1 day ago · Updated 14:39, 14 Apr 2024. . . Bookmark. A mum has died after a stomach ache she put down to food and drinks on her hen do turned out to be terminal bowel cancer. Sam Woodcock was diagnosed ... city of buckley design standardsWebDec 4, 2024 · Introduction. Gastric cancer (GC) is one of the most common gastrointestinal tract cancers. It is a leading cause of cancer-related mortality worldwide and resulted in 782,685 deaths in 2024. 1 Because of the lack of specific symptoms, most patients present at the time of diagnosis with lymph node and distant metastasis, resulting in poor … donate clothes to womenWebApr 30, 2024 · For instance, KLF5-activated lncRNA NEAT1 accelerated gastric cancer progression via serving as a scaffold for BRG1 to down-regulate GADD45A expression . KLF5-regulated lncRNA RP1 contributed to cell proliferation and metastasis in breast cancer through suppressing p27kip1 translation . Overall, the abnormal increase of BBOX1-AS1 … donate clothing for refugeesWebThe Krüppel-like factor 5 (KLF5), a zinc-finger transcriptional factor, is highly expressed in several solid tumors, but its role in PTC remains unclear. ... Among the 1198 metastatic gastric cancer patients who started therapy within six months after metastasis detection, 87 were initially treated with trastuzumab-based chemotherapy and 1111 ... donate clothing berks countyWebMar 19, 2024 · KLF5 expression was positively related to B cells, CD8+ T cells, and macrophages in rectal cancer. In addition, KLF15 was shown to be positively linked with CD4+ T cell and macrophage levels in colon cancer patients but not in rectal cancer patients. Figure 7 city of buckley gis