Cytoplasmic translocation
WebMar 15, 2024 · To confirm whether DNA-PKcs cytoplasmic translocation specifically occurred in the tubular epithelial cells, the podocyte cell line (CIHP-1) and renal mesangial cell line (HRMC) were exposed to three types of stress. However, LPS, Cis, or chemically induced I/R did not induce DNA-PKcs translocation into the cytoplasm (fig. S1, G to L). WebJul 24, 2024 · We found that hyperosmolar, but not oxidative, stress induced robust cytoplasmic translocation of neuronal FUS, with transient nuclear clearance and loss of function. Surprisingly, this reaction is independent of stress granule formation and the molecular pathways activated by hyperosmolarity. Instead, it represents a mechanism …
Cytoplasmic translocation
Did you know?
WebMay 11, 2024 · Cytoplasmic translocation of Sirt6 occurred later, with increased polyubiquitination of p62 and apoptosis. Bafilomycin 1 (BaF1) treatment promoted … WebFeb 28, 2024 · Although the acetylation of IFI16 is crucial to its cytoplasmic translocation and downstream signal transduction, the regulation of IFI16 acetylation remains unclear. …
WebCytoplasmic translocation of TDP-43 is accompanied by reduced solubility and increased formation of protein aggregates. The cleavage takes place at amino-acid 327 between … WebJun 1, 2024 · Notably, ELAVL1 is an important RNA-binding protein that regulates mRNA stability by cytoplasmic translocation [28, 29]; therefore, we reasoned that ELAVL1 …
WebSep 10, 2024 · The cytoplasmic retention or nuclear translocation of TFEB was determined by its phosphorylation level. There were multiple phosphorylation sites on TFEB, but which phosphorylated sites were responsible for cytoplasmic retention and which dephosphorylated sites contributed to nuclear translocation were widely unknown [ 13 ]. WebAug 1, 2008 · Cytokine signaling is thought to require assembly of multicomponent signaling complexes at cytoplasmic segments of membrane-embedded receptors, in which receptor-proximal protein kinases are activated.
WebApr 8, 2024 · Considering that the nucleo-cytoplasmic translocation of histone H1 plays a crucial role in precision tumor discrimination and killing effect of ELANE/PPE, we hypothesized that accelerating ...
WebJul 14, 2024 · A Nuclear and Cytoplasmic Protein Extraction Kit was used to isolate the nuclear and cytoplasmic p53 proteins from HK-2 cells. According to the manufacturer’s recommendations, adherent cells were scraped, and the cell pellet was obtained by … batman adam west filmWebAug 1, 2008 · Cytoplasmic segments of cytokine, growth factor, and antigen receptors serve as assembly sites for complexes containing adaptor proteins, protein kinases, and … tereza macalikovaWebJan 10, 2024 · Stress-induced HMGB1 upregulation and its cytoplasmic translocation in microglia of the RVLM. Based on previous reports, HMGB1 plays a critical role in the immune response via the translocation from the nucleus to the cytoplasm, and intracellular environment to the extracellular environment [].Here, the HMGB1 expression … tereza maskova cz filmWebHu-antigen R (HuR) is a post-transcriptional regulator that belongs to the embryonic lethal abnormal vision Drosophila-like family (ELAV). HuR regulates the stability, translation, subcellular localization, and degradation of several target mRNAs, which are implicated in carcinogenesis and could affect therapeutic options. HuR protein is consistently highly … batman actor dark knightWebMay 22, 2024 · The cNLS-mediated protein transport mechanism can be conveniently divided into four steps: assembly of the cargo-carrier import complex in the cytoplasm, … tereza maskovaWebApr 9, 2024 · ZipA: A protein that connects the FtsZ ring to the bacterial cytoplasmic membrane. FtsA: An ATPase that breaks down ATP to provide energy for cell division … tereza martincova ranking wtaWebOct 6, 2024 · TDP-43 translocation from the nucleus (n) to the cytoplasm (c) was quantified based on Alexa Fluor 647 intensity (secondary antibody against TDP-43) using fluorescence microscopy and categorized into different stages (A,B) in BV-2 cells harvested 24 h (C,E) or 48 h (D,F) after transfection with either 2R or 66R plasmids in combination … batman adam west movie